Medical Chemistry - Drug Discovery Services

We provide a wide range of Drug Discovery services and solutions for innovative companies in the pharmaceutical and biotech industries.

These services include:

• Evaluating, validating and optimizing active compounds/lead candidate for a drug discovery program
• Hit-to-lead chemistry, lead optimization
• Custom focused library synthesis, synthesis to establish structure activity relationship (SAR)
• Chemistry and synthesis route development
• Synthesis of reference compounds, scaffolds, building blocks and starting materials

Aptuit Laurus can also undertake the manufacturing of small volume/clinical phase Drug Substance and Drug Product.

Additional Services

• Scaffolding, building blocks, libraries
• Focused library synthesis, synthesis to establish structure activity relationship (SAR)
• Synthesis of building blocks, scaffolds, reference compounds and intermediate compounds
• Discovery biology services
• Target identification
• Cloning (E.Coli/mammalian systems)
• Protein expression, purification, characterization
• Protein structural analysis and validation
• Library designs and synthesis
• Protein-ligand in vitro/in silico binding studies
• Protein-ligand co-crystallization
• Lead optimization and route development
• Hit-to-lead chemistry, lead optimization
• Scale-up synthesis of lead compounds